Tadalafil Daily (2.5mg / 5mg)

Daily tadalafil is a low-dose version of the same active ingredient in Cialis, taken once every day instead of before sex. Instead of timing a dose, you keep a steady level of the medication in your system.

The short answer

Daily tadalafil is a 2.5mg or 5mg tablet taken once a day so that ED treatment is always active in your body, rather than taken on demand. It reaches steady state after roughly 4–5 days of consistent dosing. It is prescription only and is not appropriate for anyone taking nitrates.

Active ingredients
Tadalafil 2.5mg or 5mg
Form
Oral tablet, once daily
Best for
Men who want to stop scheduling sex around a pill
Duration
Continuous — you're covered rather than timing a dose

Daily dosing vs. as-needed dosing

As-needed ED medication is taken before sexual activity, which means planning. Daily tadalafil removes the plan: because the drug stays at a steady level, spontaneity becomes possible again. The trade-off is that you take medication every day whether or not you have sex, and the per-dose strength is much lower.

  • Daily: 2.5mg or 5mg once a day, steady state in about 4–5 days
  • As-needed: a higher single dose taken before sexual activity
  • Daily dosing may also improve urinary symptoms from an enlarged prostate
  • Your provider chooses the approach based on your history, other medications and frequency of sex

Side effects to expect

The most commonly reported side effects of tadalafil are headache, indigestion, back or muscle aches, flushing, and nasal congestion. Back pain and muscle aches are reported more often with tadalafil than with shorter-acting PDE5 inhibitors. Most side effects are mild and fade as your body adjusts, but tell your provider about anything persistent.

Who should not take it

Do not take tadalafil if you use nitrates in any form — including nitroglycerin tablets, patches or sprays, isosorbide, or recreational 'poppers' (amyl nitrite) — or guanylate cyclase stimulators such as riociguat. Combining them can cause a sudden, dangerous drop in blood pressure. Tell your provider if you have heart disease, have had a recent heart attack or stroke, have very low or uncontrolled high blood pressure, severe liver or kidney disease, or a history of sudden vision or hearing loss.

See if it's right for you

A licensed provider reviews your intake and decides whether this treatment is appropriate. Prescription only, subject to approval.

Start Now

Compare with tadalafil vs sildenafil or read the Important Safety Information.

Read this part sober

Tadalafil and sildenafil are prescription medications. Treatment is only available after an evaluation by a licensed provider who determines it is appropriate for you. A compounded tadalafil/sildenafil rapid-dissolve tablet is prepared by a licensed compounding pharmacy and is not FDA-approved as a combination product; FDA does not review compounded drugs for safety, effectiveness, or quality.

Do not take this medication if you use nitrates (nitroglycerin, isosorbide) or guanylate cyclase stimulators such as riociguat — the combination can cause a sudden, unsafe drop in blood pressure. Seek emergency care for an erection lasting more than 4 hours. Not for use by anyone under 18, and not for women or children.